Generic medicines Questions

For example blood thining related to heart issues doctors usually recommend medicines with Acenocoumarol salt. majority of the doctors recommend the one's from big pharmaceutical companies and these are the only one's available in their hospital shops. now if u ask them about generic or some medicines which have same salt but are a little cheaper, many of them say not to take risk or simply say ki you can take but with your own responsibility. the price difference is very high between big brands and between generic ones or manufactured by companies which are not so big. what do you think about this? this is just one salt, there are many medicines having different salts and their answer is the same. do generic or small pharmaceutical companies maintain quality?

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