Generic medicines Questions
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Medicines
To invent drug like crocin it takes lot of research which needs lot of money. So the company which invented medicine creates patent for that drug/ composition so nobody can copy that. Patent is generally for 10 - 15 years. Once that expires pharma companies are free to create medicine based on that composition. As it's copy work they can create it in less cost so less price for drug. India is known for creating generic medicines which are sold all over the world even in US
Whenever it comes to LSD, go with the doctor recommended drugs and don't R&D with your body and disease. But one can use generic medicines apart from critical conditions, life saving drugs...etc
This is a question with no "single" answer. Everyone has their personal experiences, but then everyone's body mechanics is also different.
Someone asking this question means he is dealing with chronic desease, and in such cases remember few things
- Generic+alien brands can't be trusted, and if they do any damage then there in no going back in most cases, so don't experiment
- 1 day in ICU costs 50K now, that will be more expensive than year long supply
- for age 55+ It's almost impossible to gain back immunity, so don't take any risks or you will end up inviting more health issues
- Don't try to add homeopathy or naturopathy just cause you watched a video on youtube
The saving you can safely make is by choosing less expensive top tier alternatives (sun pharma and mankind are often cheaper)
Dava India is also selling genric medicine and it's best authorised
I am a Medical doctor and have done extensive practical study into this. I will suggest you to take JAN AUSHADHI generics only with govt stamp. Jan aushadhi centres and even BIG MEDICALS are selling cheap private generics because there is 900 to 1500% profit margins on these generics,and low quality material,bad manufacturing, which will surely cause you to die much sooner.
Brands like Cipla,SYSTOPIC, BLUE CROSS,UNISON are very good when it comes to cheaper branded generics. Avoid all lower generic brands like jagsonpal,johnlee, KNOLL, and every brand the shop owner gives you.
IF YOU CANT DO OWN RESEARCH AND UNDERSTAND THE PLANT IN WHICH THE MEDICINE IS BEING MANUFACTURED, ONLY GO FOR BRANDED OR BRANDED GENERICS,Avoid unknown brands.
Generics are not making the patient richer, but infact medical shop owners are selling these 3rd grande products only for profits, they never give patient good quality generics, NEVER DEPEND AND HAVE MORE FAITH IN CHEMIST THAN YOUR DOCTOR!!
Most People who are commenting here don't understand how medicines are manufactured. Cipla, McLeod, Sun, Systopic small or big or medium pharmacies can outsource manufacturing medicines but sell under their name. This is why generic medicines take long time or sometimes have no effect as the active ingredient in them is lower compared to original molecule inventor brand. Examples of paracetamol, Cetrizine, levocetrizine etc are too cheap drugs to manufacture so quality would be good even with generics. This can't be extrapolated to speciality medicines. Allegra products are vouched for their quality. Ceftum antibiotic is widely prescribed but most other brands quality is questionable. There is a reason why most doctors stick to recognised brands or original inventor brands.
For Life style diseases like BP, Diabetes, heart or major ailments stick to original inventor brand or reputed only.
Anit biotics, anti viral, anti fungal - same as above.
From my personal experience, there is too much variation in the efficacy of the generic medicines.
For 1 tablet of a branded medicine, you need 3/4 tablets of generic medicine. So, the cost remains the same while risking your life as bonus.
Central Government Health Scheme hospitals, and as name suggests only for Central Government employees and their spouse.
My point was if the efficacy of the generics were too low compared to innovator, then it would have been obvious by now.
But yeah, if its critical, better go for the brand that the doctor prescribed to avoid possible issues later in case of any complications.
It is obvious. Try using Ceftum vs Systopic same tablet or just ask doctors how fast and efficient Ceftum works. Ask an eye specialist how efficient the brand Allegran is. Quality comes at a price. This is universal truth.
remember pfizer vaccines? Remember countries buying indian medicine during covid? It was generic which saved everyone. This debate is not worth. The drugs produced should be tested for quality. Just a few days back many kids died due to a cough syrup. So it has both sides, but if left to big countries and big pharma industry, we all will die without medicine. It will create a humanitarian crisis if generics are removed,
Generics sold in India unlike those approved by the FDA need not be chemically equivalent to the original drug and until 2017 even bio-equivalence wasn't mandated. https://twitter.com/PriyankaPulla/status/169061...
JIPMER did a study on efficacy of the innovator drug Itraconazole vs generics and the results weren't pretty to say the least. https://onlinelibrary.wiley.com/doi/abs/10.1111...
Itraconazole by J&J is accepted by physicians to be superior but it has now been pushed out of the market.
Hello all, let's understand the basics between Innovator vs Generic Vs Branded Generic:
1. Innovator: An innovator is someone who comes up with new and creative ideas. In the context of products, it refers to a company or individual who creates something completely new and unique. Innovators are like pioneers, exploring new territory and introducing fresh concepts to the world.
Sad fun fact: Not a single Indian company is innovator companies till date.( I have attached the image of top 10)
Dr Reddy's might become one in coming years.
2. Generic: When something is called "generic," it means it's a basic, unbranded version of a product. It doesn't have any special name or fancy packaging. Think of it like plain cereal without a colorful box or a simple shirt without a famous logo. It's usually more affordable, but it might not have any special features or extra benefits.
3. Branded Generic: This is like a mix between generic and branded products. It's a version of a product that is made by a different company but still carries a recognizable brand name. For example, a popular medicine might have a branded version made by a well-known company and a branded generic version made by a different company. The branded generic is usually less expensive than the original branded version but might still have some recognition because of the brand name.
In short, innovators create new things, generics are basic and unbranded, and branded generics are a mix of affordability and a familiar brand name.
Tip: Go for companies which are USFDA certified.
I am working in pharmaceutical company as a assistant manager of quality control. And i would recommend to always take big brand medicine like sunpharma, cipla, intas, zydus, biocon etc.. when it's about life saving drugs because as you mentioned blood thinning drug is costly and yes it's costly due to API is also costly and big brand never take risk because it can close it's entire company is this kind of market complaint prove that they used inferior API hence they always purchase raw materials from direct reputed company and also check from them side, but in case of small companies they always purchase raw materials from non reputed companies due to save money and also quality control is not good even they use failed raw materials in drug to save cost, that's why always prefer life saving drugs from big pharma companies, even manufacturers it self should them only not marketed by them and manufactured by others....
Generic is affect lesser than branded u can check by any of gas or pain killer also
Government's instructions to doctors, said- If generic medicine is not written, action will be taken
Honestly the branded medicines are recommended because they are promoted by big companies and offer commission to Doctors and international trips and great gifts. Still they can be better, but however generic too are good. It depends on the generic company too
So do one thing
Download - Tata 1MG app from Play Store
Search for the medicine prescribed.
Below that you will get alternative generic names with price difference, go for the one that is atleast in the middle cost market and not very cheap. You can click on them and check how many people bought it.if more have bought, that means it is good.
So, no harm in buying generic. Medical Industry is a big scam, and we all saw it first hand in the COVID times.
I am using JA stores for medicines of all kind. Found no side effect of whatsoever. Why not JAs than any other generic salts?
Fantastic article: https://www.livemint.com/politics/policy/how-we...
Drug regulation in India has been broken for decades.
From the article: "Meanwhile, the Maharashtra Food and Drugs Administration will prosecute a manufacturer only if the active ingredient is less than 30% of the labelled amount. Gujarat has the lowest bar of all, and will only prosecute spurious and adulterated drugs.
Finally, none of these states will prosecute dissolution, disintegration or impurity failures because they deem them minor.
But there is a major flaw with this rationale: the distinction it makes between minor and major offences isn’t scientific. A drug with active ingredient less than the mandated 90-95% can, in fact, be as dangerous as a drug with active ingredient less than 30%. For instance, from the point of view of antimicrobial resistance—a major public health scourge today—an antibiotic with 70% active ingredient is more dangerous than one with none at all.
Nor are dissolution, disintegration, and impurity failures to be sneezed at. A patient taking a tablet of the enzyme levothyroxine to control hypothyroidism will fall ill if the tablet doesn’t dissolve. Impurities such as arsenic and lead, which can easily creep into drugs, are life-threatening. And an antiplatelet drug that doesn’t disintegrate in one’s body won’t protect a person having a heart attack."
much like cibil for credit score
See Nitrosamine contamination issue in USA.
Reputed Pharma companies from India were pulled up.
In India the FDA is not centralised like USA. Each state has their own FDA.
A reputed diabetic doctor told me that some Pharma companies in UP, Bihar etc just put chalk powder in all the medicine and sell. You will never get better with them.
Cheap is cheap for reason.
But expensive doesn't mean quality.
Many so called quality Pharma companies had to deal with impurities that cause Cancer like Nitrosamine.
USA FDA is very strict. They just put import ban on plants which don't do quality manufacturing.
Ever heard of Indian Pharma companies banned in any state by FDA.
There are many cases like Maiden Pharma cough syrup deaths in Gambia waiting to happen.
It depends on medicine. If it's a medicine for cold or pain or something acute, generic will do.
For something like diabetes or BP or heart issues avoid generics.
I am investor in many Pharma companies in share market so I know all this.
Can we trust portals like truemeds for generic medicine requirements? And I'd like to get some idea on what all brands we can trust for generics in India? Are brands such as Knoll, Zydus, Zuventus, Prevego, Ajanta Pharma, Chemo Health, Morepen Laboratories, etc reliable or someone has experienced these brands?
I would suggest to pick drugs which are marketed by some known brands like mankind pharma,cipla,merck etc.
Here the drug is manufactured by some company but marketed by known big company.
So a big brand is marketing generic drug so that they will do check efficiency of drug. Its my opinion
Yet again drugs by some of the biggest generic manufacturers failed(sub-standard/NSQ) tests by the CDSCO .
Good new in the offing. Theliverdr on Twitter has announced that he is getting a few commonly used generic medicines tested and if circumstances demand it would be expanded to cover more meds. https://twitter.com/theliverdr/status/169690827...
Additional information plus National Drugs Survey 2014-16 https://theprint.in/health/kerala-doctors-resea...
Good thread
Good share.
Go With Mankind ones.Cheaper than many company medicines and quality is decent as it's one of the top pharma companies in India.